Head to Head
| NCAAF | 2021/10/16 16:00 | Ohio v Buffalo | W | 26-27 |
| NCAAF | 2019/10/05 19:30 | Ohio v Buffalo | L | 21-20 |
| NCAAF | 2018/11/15 00:00 | Buffalo v Ohio | L | 17-52 |
| NCAAF | 2017/11/24 18:00 | Ohio v Buffalo | W | 24-31 |
| NCAAF | 2016/11/03 22:00 | Buffalo v Ohio | L | 10-34 |
| NCAAF | 2015/10/24 19:30 | Buffalo v Ohio | W | 41-17 |
| NCAAF | 2014/11/06 01:00 | Ohio v Buffalo | L | 37-14 |
| NCAAF | 2012/10/06 12:00 | Ohio v Buffalo | L | 38-31 |
Home History
| NCAAF | 2022/10/22 17:00 | Toledo v Buffalo | W | 27-34 |
| NCAAF | 2022/10/15 17:00 | Buffalo v Massachusetts | W | 34-7 |
| NCAAF | 2022/10/08 16:00 | Buffalo v Bowling Green | W | 38-7 |
| NCAAF | 2022/10/01 19:30 | Miami Ohio v Buffalo | W | 20-24 |
| NCAAF | 2022/09/24 16:00 | Buffalo v Eastern Michigan | W | 50-31 |
| NCAAF | 2022/09/17 17:00 | Buffalo v Coastal Carolina | L | 26-38 |
| NCAAF | 2022/09/10 22:00 | Holy Cross v Buffalo | L | 37-31 |
| NCAAF | 2022/09/03 16:00 | Buffalo v Maryland | L | 10-31 |
Away History
| NCAAF | 2022/10/22 18:00 | Northern Illinois v Ohio | W | 17-24 |
| NCAAF | 2022/10/15 19:30 | Ohio v Western Michigan | W | 33-14 |
| NCAAF | 2022/10/08 18:00 | Akron v Ohio | W | 34-55 |
| NCAAF | 2022/10/01 19:30 | Ohio v Kent State | L | 24-31 |
| NCAAF | 2022/09/24 18:00 | Fordham v Ohio | W | 52-59 |
| NCAAF | 2022/09/17 18:00 | Ohio v Iowa State | L | 10-43 |
| NCAAF | 2022/09/10 16:00 | Ohio v Penn State | L | 10-46 |
| NCAAF | 2022/09/03 22:00 | Florida Atlantic v Ohio | W | 38-41 |