| Challenger Marbella | 10/26 13:10 | 25 | [183] Mario Vilella Martinez v Pedro Martinez [93] | 2-6,1-6 | |
| Challenger Alicante | 10/17 09:00 | 28 | [158] Carlos Alcaraz v Mario Vilella Martinez [188] | 1-6,6-3,6-4 | |
| Challenger Alicante | 10/16 11:45 | 27 | [174] Steven Diez v Mario Vilella Martinez [188] | 3-6,2-6 | |
| Challenger Alicante | 10/15 12:35 | 26 | [188] Mario Vilella Martinez v Malek Jaziri [251] | 6-3,6-2 | |
| Challenger Alicante | 10/13 11:55 | 25 | Diego A B Sanchez v Mario Vilella Martinez | 3-6,2-6 | |
| Challenger Barcellona | 10/08 10:30 | 26 | [189] Carlos Alcaraz v Mario Vilella Martinez [183] | 6-3,4-6,6-2 | |
| Challenger Barcellona | 10/05 11:05 | 25 | [193] Aleksandar Vukic v Mario Vilella Martinez [183] | 6-2,3-6,6-7 | |
| Open di Francia | 09/23 13:45 | 15 | [182] Mario Vilella Martinez v Daniel Elahi Galan [152] | 6-7,0-6 | |
| Open di Francia | 09/21 15:40 | 14 | [118] Evgeny Donskoy v Mario Vilella Martinez [180] | 3-6,5-7 | |
| Challenger Cordenons | 09/03 15:00 | 26 | [199] Andrea Collarini v Mario Vilella Martinez [170] | 6-2,6-4 | |
| Challenger Cordenons | 09/02 12:00 | 25 | [170] Mario Vilella Martinez v Lorenzo Giustino [154] | 6-4,2-6,6-4 | |
| Challenger Trieste | 08/29 08:00 | 28 | [183] Mario Vilella Martinez v Riccardo Bonadio [408] | 6-7,2-6 | |
| Challenger Trieste | 08/28 10:00 | 27 | [212] Liam Broady v Mario Vilella Martinez [183] | 7-6,4-6,4-6 | |
| Challenger Trieste | 08/27 08:00 | 26 | [183] Mario Vilella Martinez v Yannick Hanfmann [116] | 4-6,6-3,6-2 | |
| Challenger Trieste | 08/25 13:50 | - | [354] Giulio Zeppieri v Mario Vilella Martinez [183] | 1-6,3-6 | |
| Challenger Todi | 08/19 11:30 | 26 | [188] Mario Vilella Martinez v Antoine Hoang [136] | 6-4,3-6,4-6 | |
| Challenger Todi | 08/17 18:10 | - | [282] Andrea Arnaboldi v Mario Vilella Martinez [188] | 3-6,6-7 | |
| Spagna - Lega estiva | 07/16 08:30 | - | Mario Vilella Martinez v Pol M Tiffon | 5-7,3-6 | |
| UTR Pro Tennis Series Spagna | 07/12 15:00 | - | [188] Mario Vilella Martinez v Jaume Munar [105] | 6-3,1-6,0-0 | |
| UTR Pro Tennis Series Spagna | 07/11 14:30 | - | [175] Carlos Taberner v Mario Vilella Martinez [188] | 4-6,6-4,0-0 | |
| ATP Rio de Janeiro | 02/15 20:35 | 64 | Mario Vilella Martinez v Filip Horansky | 6-7,3-6 | |
| ATP Buenos Aires | 02/08 14:30 | 64 | [179] Mario Vilella Martinez v Jozef Kovalik [130] | 6-3,0-6,4-6 | |
| ATP Cordoba | 02/01 19:00 | 64 | [135] Facundo Bagnis v Mario Vilella Martinez [196] | 1-6,6-2,6-1 | |
| Challenger Punta del Este | 01/29 17:30 | 25 | Renzo Olivo v Mario Vilella Martinez | 7-5,6-1 | |
| Australian Open | 01/21 02:00 | 23 | [196] Mario Vilella Martinez v Karen Khachanov [17] | 6-4,4-6,6-7,3-6 | |
| Australian Open | 01/18 01:30 | 46 | [239] Mathias Bourgue v Mario Vilella Martinez [196] | 1-6,4-6 | |
| Australian Open | 01/16 23:00 | 45 | [196] Mario Vilella Martinez v Facundo Bagnis [135] | 7-6,0-6,6-4 | |
| Australian Open | 01/16 01:10 | 44 | [196] Mario Vilella Martinez v Nicolas Mahut [191] | 6-3,6-4 | |
| Challenger Noumea | 01/06 00:30 | 24 | [216] Hiroki Moriya v Mario Vilella Martinez [193] | 7-5,6-3 | |
| Challenger Montevideo | 11/07 18:35 | 26 | [181] Mario Vilella Martinez v Andrej Martin [113] | Retired |