| Challenger Montevideo | 11/06 14:00 | 25 | [181] Mario Vilella Martinez v Filip C Jianu [447] | 6-2,5-7,6-4 | |
| Challenger Guayaquil | 10/29 23:00 | 25 | [179] Mario Vilella Martinez v Roberto Quiroz [268] | 7-6,5-7,2-6 | |
| Challenger Lima | 10/24 18:05 | 26 | [131] Federico Coria v Mario Vilella Martinez [179] | 6-2,6-1 | |
| Challenger Lima | 10/22 16:30 | 25 | [347] Pedro Sakamoto v Mario Vilella Martinez [179] | 6-4,3-6,6-7 | |
| Challenger Santo Domingo | 10/10 23:00 | 26 | [181] Mario Vilella Martinez v Alejandro Tabilo [224] | 6-3,0-6,3-6 | |
| Challenger Santo Domingo | 10/08 17:00 | 25 | [181] Mario Vilella Martinez v Maxime Hamou [371] | 6-2,6-1 | |
| Challenger Firenze | 09/27 09:00 | 27 | [205] Marco Trungelliti v Mario Vilella Martinez [191] | 4-6,6-3,7-6 | |
| Challenger Firenze | 09/26 11:10 | 26 | [177] Filip Horansky v Mario Vilella Martinez [191] | 1-6,1-6 | |
| Challenger Firenze | 09/25 11:30 | 25 | [191] Mario Vilella Martinez v Martin Klizan [121] | Retired | |
| Challenger Firenze | 09/24 10:50 | 24 | [340] Daniel Gimeno-Traver v Mario Vilella Martinez [191] | 6-7,2-6 | |
| Challenger Biella | 09/19 11:30 | 26 | [191] Mario Vilella Martinez v Andrea Collarini [219] | 7-6,4-6,2-6 | |
| Challenger Biella | 09/18 08:00 | 25 | [191] Mario Vilella Martinez v Raul Brancaccio [283] | 6-1,6-4 | |
| Challenger Siviglia | 09/12 11:00 | 26 | [190] Mario Vilella Martinez v Guillermo Garcia-Lopez [150] | 6-1,6-7,4-6 | |
| Challenger Siviglia | 09/11 16:55 | 25 | [190] Mario Vilella Martinez v Javier Barranco Cosano [298] | 7-6,7-6 | |
| Challenger Maiorca | 08/28 08:00 | 25 | [342] Botic Van De Zandschulp v Mario Vilella Martinez [202] | Retired | |
| US Open | 08/23 18:30 | 46 | [202] Mario Vilella Martinez v Jannik Sinner [131] | 6-7,0-6 | |
| US Open | 08/22 17:25 | 45 | [202] Mario Vilella Martinez v Akira Santillan [242] | 6-7,6-4,6-2 | |
| US Open | 08/20 19:25 | 44 | [117] Taro Daniel v Mario Vilella Martinez [202] | 6-7,7-6,4-6 | |
| Challenger Augsburg | 08/08 10:35 | 26 | [313] Julian Lenz v Mario Vilella Martinez [207] | 6-1,6-2 | |
| Challenger Augsburg | 08/06 12:55 | 25 | [343] Peter Heller v Mario Vilella Martinez [207] | 2-6,2-6 | |
| Challenger Liberec | 07/30 08:00 | 24 | [366] Zsombor Piros v Mario Vilella Martinez [208] | 6-1,4-6,6-4 | |
| Challenger Praga | 07/28 13:00 | 29 | [428] Chun Hsin Tseng v Mario Vilella Martinez [266] | 4-6,2-6 | |
| Challenger Praga | 07/27 11:20 | 28 | [266] Mario Vilella Martinez v Carlos Taberner [335] | 7-5,6-2 | |
| Challenger Praga | 07/26 13:30 | 27 | [266] Mario Vilella Martinez v Lorenzo Giustino [137] | 6-0,7-6 | |
| Challenger Praga | 07/25 11:35 | 26 | [266] Mario Vilella Martinez v Attila Balazs [141] | 6-4,6-3 | |
| Challenger Praga | 07/24 11:45 | 25 | [202] Aleksandr Nedovyesov v Mario Vilella Martinez [266] | 2-6,1-6 | |
| Challenger Praga | 07/22 14:30 | 24 | Martin Damm v Mario Vilella Martinez | 1-6,1-6 | |
| Challenger Perugia | 07/09 10:20 | 25 | [160] Alessandro Giannessi v Mario Vilella Martinez [269] | 6-7,6-2,6-3 | |
| Challenger Perugia | 07/08 12:20 | 24 | [269] Mario Vilella Martinez v Daniel Gimeno-Traver [244] | 6-3,5-7,6-2 | |
| Challenger Milano | 06/25 14:40 | 25 | [329] Martin Cuevas v Mario Vilella Martinez [262] | 6-3,2-6,6-4 |